Novel Conjugates Properties Chitosan Acid Abts Scavenging Capacities Power

Both CGA-CS and PLA-CS showed excellent lipid and protein oxidation inhibition capabilities the conjugates were proved to have significant antibacterial issues against four common pathogenic bacteriums: Pseudomonas fluorescens, Pseudomonas aeruginosa, Pseudomonas putida, and Staphylococcus aureus (P < 0) The newly synthesized water-soluble polyphenol-chitosan conjugates showed remarkable biological activity, particularly CGA-CS. This study extends new brainstorms and a strong theoretical foundation for geting natural food preservation textiles with potential applications in the food industry. © 2024 Society of Chemical Industry.The effect of chitosan type and drug-chitosan ratio on physical characteristics and release profile of ketoprofen microparticles prepared by spray drying.objects: In order to minimize gastrointestinal irritation and to extend the absorption of ketoprofen, microparticles fixed with chitosan have been trained. In this study, chitosan type and drug-chitosan ratio were enquired to prepare microparticles of ketoprofen and measured for physical characteristics and drug release profiles Microparticles were developed by utilising ionic gelation methods with chitosan, which has two different viscousnessses i.

e., 19 and 50 cPs, cross-united with tripolyphosphate, and dried by spray drying method. The microparticles were made with a drug-chitosan ratio of 5:15 and 6:15 The upshots evinced that the microparticles had spherical builds. Increasing the amount of ketoprofen ameliorated the drug content and entrapment efficiency. Evaluation of drug release in simulated intestinal fluid (pH 6) showed that the microparticles maked with chitosan 19 cPs had the slowest release rate than those of chitosan 50 cPs, while that of the microparticles machinated with chitosan 50 cPs with the ratio of drug/polymer 6:15 was the fastest, as rendered by its slope value.  vitamin d3 deficiency  of microparticles with chitosan 19 cPs was slower than those microparticles with chitosan 50 cPs. CONCLUSIONS: It could be proposed that by increasing the amount of ketoprofen, it improved the entrapment efficiency and the release rate of microparticles.

Nanocomposite chitosan dressing comprising polydopamine‑copper Janus nanoparticle.This research aims to introduce a new wound dressing with antibacterial and anti-inflammatory properties made from chitosan and copper-comprising Janus nanoparticles (JNPs). The JNPs were synthesised by attaching copper to PDA nanospheres, which were then engrafted in Chitosan at different concentrations. The resulting spherical JNPs had a mean size of 208 ± 96 nm, and EDX mapping showed successful adhesion of Cu(2+) ions to PDA nanospheres with a total Cu(2+) content of 16 wt%. The samplings displayed complected porous constructions, increasing JNPs concentration leading in larger pore size and higher porosity. The addition of JNPs to 10 % (Ch-JNP 10) leaved in the highest strength, young modulus, and crystallinity, while a reverse trend was mentioned at higher JNPs content. JNPs improve the antibacterial activity of chitosan-based dressing, especially against E.

coli. All samplings were biocompatible and did not exhibit any cytotoxic effects. Ch-JNP10 had higher cellular density, confluency, and collagen secretion than other samples. The in vivo study marched that Ch-JNP10 hastened epithelialization and oriented collagen fiber formation while slenderizing inflammation Ch-JNP10 may be a potential wound raimenting for chronic woundings.Formation of Alginate/Chitosan Interpenetrated Networks Revealed by EPR Spectroscopy.This study studies the physico-chemical properties of interpenetrated polymer networks (IPNs) and semi-IPN leading from cross-linking chitosan with glutaraldehyde and alginate with Ca(2+) cations, as a function of the order in which the cross-linking agents are added to the polymer mixture.  Order now -chemical methods were used to assess the conflicts between organisations: rheology, IR spectroscopy, and electron paramagnetic resonance (EPR) spectroscopy.