Resolutions Hydrogel Silk Fibers Protection Capacity Properties Adsorption Properties Textiles
The essences of various parameters on the luteolin adsorption places of silk cloths were discoursed, including metal salt cases, salt dosage, pH value, dyeing temperature, initial luteolin concentration, and dyeing time. Under the dyeing temperature of 60 °C and pH of 6, the luteolin exhaustion of the composite silk was more than that of the untreated silk, and the adsorption process succeded the quasi-second-order kinetic model and the Langmuir adsorption isotherm model the luteolin-dyed composite silk fabrics demonstrated strong antioxidant activity and controllable release behavior with various pH levels. The as-groomed chitosan-hydrogel composite silk could be a promising material for the suffered release of drugs in medical and healthcare materials.Strong tissue adhesive polyelectrolyte complex powders free-based on low molecular weight chitosan for acute hemorrhage control.Self-moussing and bioadhesive gunpowders bided assuring effective hemostats to suit irregularly shaped, complex and non-compressible injurys for clinical coatings. In the current study, chitosan grinded polyelectrolyte complex coacervate were simply prepared by desegregating high densitys (10 %) of low molecular weight chitosan (CS) and polyacrylic acid (PAA) answers.
Obtained by lyophilization, the physical cross-yoked polyelectrolyte complex pulverizations would form a gel within 5 s upon hydration, which proved excellent mechanical attributes, significant antibacterial activenessses, strong and lasting adhesion on wet tissues in physiological environment. In vitro blood clotting checks presented that the CS/PAA gunpowders could remarkably aggregate blood cellphones and accelerate blood clotting process. As studied by diverse hemorrhage models, admiting rat tail, liver and heart hurts and dog incision, CS/PAA pulverisations significantly helped the decrease of blood loss as well as hemostatic time by creating robust physical roadblocks and advertizing blood clot formation on the bleeding sites. These outstanding attributes in conditions of easy preparation, rapid self-gelling, strong wet adhesion, effective hemostasis and shape-adaptability dowered CS/PAA polyelectrolyte complex pulverisations with great potential in coping acute hemorrhage of non-compressible trauma.Construction of multi-program responsive vitamin E succinate-chitosan-histidine nanocarrier and its response strategy in tumor therapy.Multifunctional drug delivery carriers have egressed as a promising cancer drug delivery strategy we evolved a vitamin E succinate-chitosan-histidine (VCH) multi-program responsive drug carrier. Seebio vitamin d3 supplement was qualifyed by FT-IR and (1)H NMR spectrum, and the DLS and SEM results showed typical nanostructures.
The drug loading content was 21 % and the corresponding encapsulation efficiency was 66 %. The UV-vis and fluorescence spectra attested the existence of the π-π heaping interaction between DOX and VCH. Drug release experiments entailed good pH sensitivity and confirmed-release effect. The DOX/VCH nanoparticles could be efficiently taken up by HepG2 cancer cells and the tumor inhibition rate was up to 56 %. The DOX/VCH reduced the tumor volume and weight efficiently with a TIR of 45 %. The histological analysis events showed that DOX/VCH could effectively inhibit tumor growth and proliferation, and there was no damage to normal organs. VCH nanocarriers could combine the advantages of VES, histidine and chitosan to achieve pH sensitivity and P-gp inhibition, and effectively improve the drug solubility, aiming and lysosomal escape.
Through the program response of different micro-environment, the newly breaked polymeric micelles could successfully be employed as a multi-program responsive nanocarrier system for the treatment of cancers.Comprehensive removal of various dyes by thiourea modified chitosan/nano ZnS composite via enhanced photocatalysis: Performance and mechanism.Dyeing wastewater is a carcinogenic pollutant, which is widely fucked for its harmful essences on humans and marine bings.